isocitrate dehydrogenase (NADP+) activity

Term ID

GO:0004450

Synonyms

• dual-cofactor-specific isocitrate dehydrogenase activity
• isocitrate (NADP) dehydrogenase activity
• isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
• isocitrate dehydrogenase (NADP) activity
• isocitrate dehydrogenase (NADP-dependent) activity
• isocitrate:NADP+ oxidoreductase (decarboxylating)
• NADP isocitric dehydrogenase activity
• NADP(+)-ICDH activity
• NADP(+)-IDH activity
• NADP(+)-linked isocitrate dehydrogenase activity
• NADP-dependent isocitrate dehydrogenase activity
• NADP-dependent isocitric dehydrogenase activity
• NADP-linked isocitrate dehydrogenase activity
• NADP-specific isocitrate dehydrogenase activity
• triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity

Definition

Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

References

• EC:1.1.1.42
• MetaCyc:ISOCITDEH-RXN
• RHEA:19629
• Reactome:R-HSA-389540
• Reactome:R-HSA-389550
• Reactome:R-HSA-450984

Ontology

GO: Molecular Function    QuickGO    AmiGO