glycine dehydrogenase (decarboxylating) activity

Term ID

GO:0004375

Synonyms

• glycine cleavage system P-protein activity
• glycine decarboxylase activity
• glycine-cleavage complex
• glycine-cleavage complex P-protein activity
• glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)
• glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)
• P-protein
• protein P1

Definition

Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H+ = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2.

References

• EC:1.4.4.2
• MetaCyc:GCVP-RXN
• RHEA:24304
• Reactome:R-HSA-5693967

Ontology

GO: Molecular Function    QuickGO    AmiGO