tetrahydrofolylpolyglutamate synthase activity

Term ID

GO:0004326

Synonyms

• folate polyglutamate synthetase activity
• folylpoly(gamma-glutamate) synthase activity
• folylpoly-gamma-glutamate synthase activity
• folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity
• folylpolyglutamate synthase activity
• folylpolyglutamate synthetase activity
• folylpolyglutamyl synthetase activity
• formyltetrahydropteroyldiglutamate synthetase activity
• FPGS activity
• N(10)-formyltetrahydropteroyldiglutamate synthetase activity
• N10-formyltetrahydropteroyldiglutamate synthetase activity
• tetrahydrofolate synthase activity
• tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity
• tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)
• tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)

Definition

Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1). 6.3.2.17

References

• EC:6.3.2.17
• MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN
• RHEA:10580
• Reactome:R-HSA-197958
• Reactome:R-HSA-200681
• Reactome:R-HSA-200682

Ontology

GO: Molecular Function    QuickGO    AmiGO