RNA polymerase I preinitiation complex assembly

Term ID

GO:0001188

Synonyms

• RNA polymerase I transcriptional preinitiation complex assembly
• RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript
• RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript

Definition

The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides. 14969726

References

Ontology

GO: Biological Process    QuickGO    AmiGO