chromosome conformation-based evidence

Term ID

ECO:0000232

Synonyms

3C
chromosome conformation capture
chromosome conformation capture-based evidence

Definition

A type of experimental evidence that is based on a five-step technique of cross-linking DNA in vivo, restriction digestion, intramolecular ligation, reversing DNA cross-links, DNA processing, and quantitation that serves to analyze the spatial organization of chromatin in a cell and quantify the number of interactions between genomic loci that are nearby in 3-D space.

References

Ontology

Evidence Ontology

Relationships

is a type of: experimental evidence

experimental evidence Show first 5 Terms
has subtype: 3C evidence 3C-seq evidence 4C evidence 5C evidence chromosome conformation-based evidence used in automatic assertion ... Show All 7 Terms

3C evidence 3C-seq evidence 4C evidence 5C evidence chromosome conformation-based evidence used in automatic assertion chromosome conformation-based evidence used in manual assertion Hi-C evidence Show first 5 Terms