subacute sclerosing panencephalitis

Term ID

DOID:8970

Synonyms

• Dawson's encephalitis
• Dawson's inclusion body encephalitis
• immunosuppressive measles encephalitis
• SSPE
• subacute sclerosing leukoencephalopathy
• Van Bogaert's sclerosing leukoencephalitis

Definition

A viral encephalitis that has_material_basis_in persistent central nervous system infection of the wild-type measles virus (Morbillivirus hominis) characterized by onset of personality or behavioral changes and intellectual deterioriation years after initial infection, followed by progressive decline in motor function, akinetic mutism or coma, and death. Higher incidence or shorter latency periods may be observed in those initially infected under the age of 2 or in cases of intrafamilial transmission. (6)

References

• GARD:7708
• ICD10CM:A81.1
• ICD9CM:046.2
• MESH:D013344
• MIM:260470
• NCI:C85171
• ORDO:2806
• SNOMEDCT_US_2025_09_01:192685000
• UMLS_CUI:C0038522

Ontology

Human Disease   ( DOID:8970 )