Search Ontology:
ChEBI
givinostat
- Term ID
- CHEBI:94187
- Synonyms
-
- (6-((diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate
- [6-[(diethylamino)methyl]naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate
- gavinostat
- givinostat
- givinostatum
- ITF 2357
- ITF-2357
- ITF2357
- {6-[(diethylamino)methyl]naphthalen-2-yl}methyl [4-(hydroxycarbamoyl)phenyl]carbamate
- Definition
- A member of the class of naphthalenes that is naphthalene substituted by ({[4-(hydroxycarbamoyl)phenyl]carbamoyl}oxy)methyl and (diethylamino)methyl groups at positions 2 and 6, respectively. It is a histone deacetylase inhibitor indicated for individuals diagnosed with Duchenne muscular dystrophy.
- References
-
- CAS:497833-27-9
- DrugBank:DB12645
- HMDB:HMDB0252732
- KEGG:D12742
- LINCS:LSM-4807
- PDBeChem:QCM
- PMID:20560970
- PMID:22781793
- PMID:27833530
- PMID:30474756
- PMID:31346710
- PMID:31755702
- PMID:32693648
- PMID:33682427
- PMID:34136349
- PMID:34197911
- PMID:34341511
- PMID:35571097
- PMID:35740641
- PMID:35894303
- PMID:35955430
- PMID:36009541
- PMID:36108615
- PMID:36397155
- PMID:36445551
- PMID:36793108
- PMID:36793492
- PMID:36854532
- PMID:37298104
- PMID:37306105
- PMID:37841928
- PMID:38316447
- PMID:38327117
- PMID:38430220
- PMID:38508835
- Wikipedia:Givinostat
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Phenotype
Phenotype resulting from givinostat
Phenotype where environments contain givinostat
Phenotype modified by environments containing givinostat
Human Disease Model