Search Ontology:
ChEBI

linifanib

Term ID
CHEBI:91435
Synonyms
  • 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
  • ABT 869
  • ABT-869
  • ABT869
  • linifanib
  • linifanibum
  • N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea
(all 7)
Definition
A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 2-fluoro-5-methylphenyl group, while the other is substituted by a p-(3-amino-1H-indazol-4-yl)phenyl group. It is a potent, selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinases.
References
(all 16)
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from linifanib
Phenotype where environments contain linifanib
Phenotype modified by environments containing linifanib
Phenotype affecting linifanib
Human Disease Model
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