alectinib

Term ID

CHEBI:90936

Synonyms

9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
AF 802
AF-802
alectinib
CH 5424802
CH5424802

(all 6)

Definition

An organic heterotetracyclic compound that is 6,6-dimethyl-5,6-dihydro-11H-benzo[b]carbazol-11-one carrying additional cyano, 4-(morpholin-4-yl)piperidin-1-yl and ethyl substituents at positions 3, 8 and 9 respectively. Used (as the hydrochloride salt) for the treatment of patients with anaplastic lymphoma kinase-positive, metastatic non-small cell lung cancer.

References

(all 28)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ketone morpholines nitrile organic heterotetracyclic compound piperidines

aromatic ketone morpholines nitrile organic heterotetracyclic compound piperidines Show first 5 Terms
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor

antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: alectinib(1+)

alectinib(1+) Show first 5 Terms
is_conjugate_base_of: alectinib(1+)

alectinib(1+) Show first 5 Terms

Phenotype

Phenotype resulting from alectinib

Phenotype where environments contain alectinib

Phenotype modified by environments containing alectinib

Phenotype affecting alectinib

Human Disease Model