Search Ontology:
ChEBI

tenofovir alafenamide

Term ID
CHEBI:90926
Synonyms
  • GS 7340
  • GS-7340
  • propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate
  • TAF
  • tenofovir alafenamide
Definition
An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from tenofovir alafenamide
Phenotype where environments contain tenofovir alafenamide
Phenotype modified by environments containing tenofovir alafenamide
Phenotype affecting tenofovir alafenamide
Human Disease Model
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