Search Ontology:
ChEBI

BMS-453

Term ID
CHEBI:90739
Synonyms
  • 4-[(E)-2-(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid
  • BMS 189453
  • BMS 453
  • BMS-189453
  • BMS189453
  • BMS453
Definition
A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from BMS-453
Phenotype where environments contain BMS-453
Phenotype modified by environments containing BMS-453
Human Disease Model
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