Ro 41-5253

Term ID

CHEBI:90706

Synonyms

• 4-{(1E)-2-[7-(heptyloxy)-4,4-dimethyl-1,1-dioxido-3,4-dihydro-2H-1-benzothiopyran-6-yl]prop-1-en-1-yl}benzoic acid
• LG-629
• LG629
• Ro-41-5253

Definition

A thiochromane that is 3,4-dihydro-2H-1-benzothiopyran S,S-dioxide in which the hydrogens at position 4 are both replaced by methyl groups, the hydrogens at position 7 is replaced by a heptyloxy group, while the hydrogen at position 6 is replaced by a 1-phenylprop-1-en-2-yl group, the phenyl group of which is substituted at the para position by a carboxy group. It is a selective antagonist for retinoic acid receptor α.

References

• cas:144092-31-9
• pubmed:23102850
• pubmed:24495389
• pubmed:25896049
• pubmed:9724098
• reaxys:8173393

Ontology

ChEBI  ( EBI )

Resources

CTD