Search Ontology:
ChEBI

U0126

Term ID
CHEBI:90693
Synonyms
  • (2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile
  • FT-1069-1
  • U 0126
  • U-0126
  • U0126
Definition
An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties.
References
  • cas:109511-58-2
  • cas:218601-62-8
  • lincs.smallmolecule:LSM-42806
  • pdb-ccd:5BM
  • pubmed:21618303
  • pubmed:22025280
  • pubmed:22052387
  • pubmed:22075021
  • pubmed:22101421
  • pubmed:22129618
  • pubmed:22182511
  • pubmed:22273495
  • pubmed:22286127
  • pubmed:22301382
  • pubmed:22313325
  • pubmed:22354777
  • pubmed:22396328
  • pubmed:24947959
  • pubmed:25363751
  • pubmed:25407271
  • pubmed:25492115
  • pubmed:25544156
  • pubmed:26349244
  • pubmed:9660836
  • reaxys:3483750
  • wikipedia.en:U0126
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from U0126
Phenotype where environments contain U0126
Phenotype modified by environments containing U0126
Phenotype affecting U0126
Human Disease Model