Search Ontology: 
        
        ChEBI
            vatalanib
- Term ID
- CHEBI:90620
- Synonyms
- 
    
        
        - CGP 79787
- CGP-79787
- CGP79787
- N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
- N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
- N-(p-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
- PTK 787
- PTK-787
- PTK/ZK
- PTK787
- vatalanib
- ZK-232934
 
- Definition
- A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.
- References
- 
    
        
        
    
    - CAS:212141-54-3
- DrugBank:DB04879
- KEGG:D06285
- LINCS:LSM-5774
- PMID:16882767
- PMID:21617019
- PMID:22197613
- PMID:22664478
- PMID:22910317
- PMID:23488610
- PMID:23700288
- PMID:24449400
- PMID:24799063
- PMID:24838014
- PMID:24939212
- PMID:25340839
- PMID:26206183
- PMID:26403354
- Reaxys:8638800
- Wikipedia:Vatalanib
 
- Ontology
- ChEBI ( EBI )
                
                    
                        Phenotype 
                    
                    
                
                
            
        
        
    
        
            
            
    
    
    
    
                
                    
                        Phenotype resulting from vatalanib
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype where environments contain vatalanib
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype modified by environments containing vatalanib
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype affecting vatalanib
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Human Disease Model
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    