savinin

Term ID

CHEBI:9044

Synonyms

• (-)-hibalactone
• (-)-savinin
• (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylene)dihydro-2(3H)-furanone
• (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)dihydrofuran-2(3H)-one
• (3E,4R)-4-[(2H-1,3-benzodioxol-5-yl)methyl]-3-[(2H-1,3-benzodioxol-5-yl)methylidene]oxolan-2-one
• hibalactone
• savinin

Definition

A lignan that is dihydrofuran-2(3H)-one (γ-butyrolactone) substituted by a 1,3-benzodioxol-5-ylmethylidene group at position 3 and a 1,3-benzodioxol-5-ylmethyl group at position 4 (the 3E,4R-isomer). It exhibits antiviral activity against SARS-CoV-2.

References

• cas:493-95-8
• chemspider:4445161
• kegg.compound:C10880
• knapsack:C00002624
• pubmed:11217086
• pubmed:12392817
• pubmed:15852488
• pubmed:17291735
• pubmed:17663539
• pubmed:18563665
• pubmed:22497733
• pubmed:27041873
• pubmed:27714269
• pubmed:28903179
• pubmed:30915141
• pubmed:32786879
• pubmed:33089730
• pubmed:33101023
• pubmed:34313197
• pubmed:34424612
• pubmed:6539809

Ontology

ChEBI  ( EBI )