Search Ontology:
ChEBI

conazole antifungal agent

Term ID
CHEBI:86323
Synonyms
  • azole antibiotic
  • azole antibiotics
  • conazole antifungal agents
Definition
A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has subtype
has_role
Phenotype
Phenotype resulting from conazole antifungal agent
Phenotype where environments contain conazole antifungal agent
Phenotype modified by environments containing conazole antifungal agent
Human Disease Model