phentolamine

Term ID

CHEBI:8081

Synonyms

• 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline
• 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol
• fentolamina
• phentolamine
• Phentolamine mesylate
• phentolaminum
• Regitina
• Regitine
• Rogitine

Definition

A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An α-adrenergic antagonist, it is used for the treatment of hypertension.

References

• cas:50-60-2
• drugbank:DB00692
• drugcentral:2142
• hmdb:HMDB0014830
• kegg.drug:D00509
• kegg.drug:D08362
• lincs.smallmolecule:LSM-4022
• patent:US2503059
• pubmed:23438114
• pubmed:23522530
• pubmed:23658874
• pubmed:23666670
• pubmed:23887290
• pubmed:23926134
• reaxys:272944
• wikipedia.en:Phentolamine

Ontology

ChEBI  ( EBI )

Resources

CTD