Search Ontology:
ChEBI
pergolide mesylate
- Term ID
- CHEBI:8021
- Synonyms
-
- (8beta)-8-[(methylsulfanyl)methyl]-6-propylergolin-6-ium methanesulfonate
- (8beta)-8-[(methylsulfanyl)methyl]-6-propylergoline methanesulfonate
- Pergolide mesilate
- pergolide methanesulfonate
- pergolide monomesylate
- pergolide monomethanesulfonate
- Permax
- Definition
- A methanesulfonate salt obtained from pergolide by mixing eqimolar amount of pergolide and methanesulfonic acid. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.
- References
-
- CAS:66104-23-2
- Chemspider:43504
- DrugBank:DBSALT002445
- KEGG:D00502
- PMID:10365192
- PMID:11257938
- PMID:12378837
- PMID:12446951
- PMID:14532675
- PMID:15257688
- PMID:15591656
- PMID:15602103
- PMID:19210262
- PMID:19801850
- PMID:20949429
- PMID:21324306
- PMID:21507864
- PMID:23966481
- PMID:24134630
- PMID:27301465
- PMID:31082785
- PMID:6889702
- PMID:7562267
- PMID:8748627
- Reaxys:5698117
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_part
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- has_role
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Phenotype
Phenotype resulting from pergolide mesylate
Phenotype where environments contain pergolide mesylate
Phenotype modified by environments containing pergolide mesylate
Human Disease Model