Search Ontology:
ChEBI
ACT-132577
- Term ID
- CHEBI:76609
- Synonyms
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- N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]sulfuric diamide
- Definition
- A member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension.
- References
- (all 12)
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_functional_parent
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- has_role
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- inverse has_functional_parent
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Phenotype
Phenotype resulting from ACT-132577
Phenotype where environments contain ACT-132577
Phenotype modified by environments containing ACT-132577
Phenotype affecting ACT-132577
Human Disease Model