Search Ontology:
ChEBI
(R)-ketorolac
- Term ID
- CHEBI:76227
- Synonyms
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- (+)-ketorolac
- (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- (R)-(+)-ketorolac
- Definition
- A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic ketorolac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
- References
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- CAS:66635-93-6
- PDBeChem:KTR
- PMID:10027870
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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- inverse has_part
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- inverse is_enantiomer_of
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- is_enantiomer_of
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Show first 5 Terms
Phenotype
Phenotype resulting from (R)-ketorolac
Phenotype where environments contain (R)-ketorolac
Phenotype modified by environments containing (R)-ketorolac
Phenotype affecting (R)-ketorolac
Human Disease Model