Search Ontology:
ChEBI

naloxone

Term ID
CHEBI:7459
Synonyms
  • (-)-naloxone
  • 1-N-Allyl-14-hydroxynordihydromorphinone
  • 17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one
  • 3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5alpha-epoxymorphinan-6-one
  • naloxona
  • naloxone
  • naloxonum
Definition
A synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from naloxone
Phenotype where environments contain naloxone
Phenotype modified by environments containing naloxone
Phenotype affecting naloxone
Human Disease Model
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