nabumetone

Term ID

CHEBI:7443

Synonyms

4-(6-Methoxy-2-naphthalenyl)-2-butanone
4-(6-Methoxy-2-naphthyl)-2-butanone
nabumetona
nabumetone
nabumetonum
Relafen

(all 6)

Definition

A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

References

(all 28)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: methoxynaphthalene methyl ketone

methoxynaphthalene methyl ketone Show first 5 Terms
has_role: cyclooxygenase 2 inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug

cyclooxygenase 2 inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug Show first 5 Terms

Phenotype

Phenotype resulting from nabumetone

Phenotype where environments contain nabumetone

Phenotype modified by environments containing nabumetone

Phenotype affecting nabumetone

Human Disease Model