Search Ontology:
ChEBI
lumiracoxib
- Term ID
- CHEBI:73044
- Synonyms
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- 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid
- COX 189
- COX-189
- COX189
- lumiracoxib
- lumiracoxibum
- Prexige
- {2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
- Definition
- An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity.
- References
-
- CAS:220991-20-8
- DrugBank:DB01283
- Drug_Central:1618
- HMDB:HMDB0015403
- KEGG:D03714
- PDBeChem:LUR
- PMID:14965322
- PMID:15311562
- PMID:15456339
- PMID:17380211
- PMID:19800190
- PMID:21688392
- PMID:22069133
- PMID:22142375
- PMID:22621454
- PMID:22732767
- Reaxys:9784107
- Wikipedia:Lumiracoxib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from lumiracoxib
Phenotype where environments contain lumiracoxib
Phenotype modified by environments containing lumiracoxib
Human Disease Model