mersacidin

Term ID

CHEBI:71658

Synonyms

• 3-{(4S,7S,8S,11R,14S,17E,20S,26S)-7-[({(15S,18R,21S,22S,25S,30aS)-22-[(N-{[(2S,3S,6R)-6-amino-2-methyl-5-oxo-1,4-thiazepan-3-yl]carbonyl}-L-phenylalanyl)amino]-25-isobutyl-15-isopropyl-21-methyl-1,4,7,10,13,16,23,26-octaoxooctacosahydro-1H-pyrrolo[2,1-u][
• M87-1551

Definition

A type-B lantibiotic containing 3-methyllanthionine and S-(2-aminovinyl)-3-methylcysteine residues and four intra-chain thioether bridges. It is obtained from Bacillus sp. HIL Y-85,54728 and is active in vivo against methicillin-resistant Staphylococcus aureus (MRSA).

References

• cas:128104-18-7
• pubmed:10818347
• pubmed:10831439
• pubmed:1500347
• pubmed:1500348
• pubmed:15282239
• pubmed:1649577
• pubmed:16980420
• pubmed:21811596
• pubmed:22296295
• pubmed:22628498
• pubmed:7737474
• reaxys:8197141

Ontology

ChEBI  ( EBI )