Search Ontology:
ChEBI
dabigatran etexilate
- Term ID
- CHEBI:70746
- Synonyms
-
- dabigatran etexilate
- ethyl N-[(2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alaninate
- Definition
- An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-β-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.
- References
-
- cas:211915-06-9
- drugcentral:776
- hmdb:HMDB0015641
- kegg.drug:D07144
- patent:US2011275824
- patent:WO2007047608
- patent:WO2011061080
- patent:WO2012027543
- patent:WO2012077136
- pubmed:21265583
- pubmed:21429525
- pubmed:21542663
- pubmed:21748501
- pubmed:21859976
- pubmed:21881389
- pubmed:22252796
- pubmed:22276081
- pubmed:22298812
- pubmed:22318514
- pubmed:22348256
- pubmed:22422743
- pubmed:22431533
- pubmed:22488474
- pubmed:22536678
- pubmed:22552763
- pubmed:22563715
- pubmed:22564134
- pubmed:22669799
- pubmed:22782539
- pubmed:22803489
- pubmed:22995531
- pubmed:23476049
- reaxys:15496119
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from dabigatran etexilate
Phenotype where environments contain dabigatran etexilate
Phenotype modified by environments containing dabigatran etexilate
Phenotype affecting dabigatran etexilate
Human Disease Model