Search Ontology:
ChEBI
regorafenib
- Term ID
- CHEBI:68647
- Synonyms
-
- 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
- BAY 73-4506
- regorafenib
- regorafenibum
- Definition
- A pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy.
- References
-
- cas:755037-03-7
- drugcentral:4654
- kegg.drug:D10138
- lincs.smallmolecule:LSM-1226
- patent:US2006058358
- patent:WO2006125540
- patent:WO2007054216
- patent:WO2007068380
- patent:WO2007068382
- patent:WO2008043446
- patent:WO2008055629
- patent:WO2008058644
- patent:WO2008089388
- patent:WO2008089389
- patent:WO2011128261
- patent:WO2011130728
- pubmed:21170960
- pubmed:21419931
- pubmed:21752724
- pubmed:22421192
- pubmed:22568966
- pubmed:22577890
- pubmed:22612461
- pubmed:22614970
- pubmed:22706543
- pubmed:22777740
- pubmed:22785409
- pubmed:22959186
- reaxys:14359949
- wikipedia.en:Regorafenib
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from regorafenib
Phenotype where environments contain regorafenib
Phenotype modified by environments containing regorafenib
Phenotype affecting regorafenib
Human Disease Model