Search Ontology:
ChEBI

enzalutamide

Term ID
CHEBI:68534
Synonyms
  • 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
  • MDV 3100
  • MDV-3100
  • MDV3100
  • XTANDI
Definition
A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer.
References
  • cas:915087-33-1
  • drugcentral:4628
  • lincs.smallmolecule:LSM-6254
  • patent:US2007254933
  • patent:WO2006124118
  • patent:WO2011106570
  • pubmed:21986558
  • pubmed:22101903
  • pubmed:22113551
  • pubmed:22162475
  • pubmed:22229405
  • pubmed:22258371
  • pubmed:22258374
  • pubmed:22266222
  • pubmed:22310230
  • pubmed:22373838
  • pubmed:22393799
  • pubmed:22411952
  • pubmed:22429837
  • pubmed:22472508
  • pubmed:22516457
  • pubmed:22710436
  • pubmed:22815001
  • pubmed:22845410
  • pubmed:22852027
  • pubmed:22894553
  • pubmed:22956944
  • pubmed:22985411
  • pubmed:22987974
  • reaxys:11718700
  • wikipedia.en:Enzalutamide
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from enzalutamide
Phenotype where environments contain enzalutamide
Phenotype modified by environments containing enzalutamide
Phenotype affecting enzalutamide
Human Disease Model