Search Ontology:
ChEBI

ruxolitinib

Term ID
CHEBI:66919
Synonyms
  • (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
  • INCB018424
  • ruxolitinib
Definition
A pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis.
References
(all 23)
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_part
Phenotype
Phenotype resulting from ruxolitinib
Phenotype where environments contain ruxolitinib
Phenotype modified by environments containing ruxolitinib
Phenotype affecting ruxolitinib
Human Disease Model
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