Search Ontology:
ChEBI

ivacaftor

Term ID
CHEBI:66901
Synonyms
  • ivacaftor
  • ivacaftorum
  • Kalydeco
  • N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
  • VX-770
Definition
An aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis.
References
  • cas:873054-44-5
  • drugcentral:4228
  • kegg.drug:D09916
  • pubmed:22047557
  • pubmed:22293084
  • pubmed:22383668
  • pubmed:22499233
  • pubmed:22508750
  • pubmed:22543461
  • pubmed:22618984
  • pubmed:22698459
  • pubmed:22723294
  • pubmed:22739718
  • pubmed:22768130
  • reaxys:11821038
  • wikipedia.en:Ivacaftor
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from ivacaftor
Phenotype where environments contain ivacaftor
Phenotype modified by environments containing ivacaftor
Phenotype affecting ivacaftor
Human Disease Model