peginesatide

Term ID

CHEBI:66889

Synonyms

• N(sup 6.21),N(sup 6.21')-(((N(sup 2),N(sup 6)-bis((omega-methoxypoly(oxyethylene))carbonyl)-L-lysyl-beta-alanyl)imino)bis(methylenecarbonyl))bis(acetylglycylglycyl-L-leucyl-L-tyrosyl-L-alanyl-L-cysteinyl-L-histidyl-L-methionylglycyl-L-prolyl-L-isoleucyl-L
• peginesatide

Definition

A heterodetic cyclic peptide composed of two identical 21-amino acid cyclic peptide units covalently bonded via a linker derived from iminodiacetic acid and β-alanine to a lysine-branched poly(ethylene glycol) chain. Used for the treatment of anemia due to chronic kidney disease in patients on dialysis.

References

• cas:913976-27-9
• kegg.drug:D09946
• pubmed:20730698
• pubmed:21290916
• pubmed:21649477
• pubmed:21710591
• pubmed:21816551
• pubmed:21940838
• pubmed:22188389
• pubmed:22192713
• pubmed:22406924
• pubmed:22592927
• pubmed:22642238
• pubmed:22683926
• pubmed:22719216
• pubmed:22745925
• wikipedia.en:Peginesatide

Ontology

ChEBI  ( EBI )