Search Ontology:
ChEBI

memantine

Term ID
CHEBI:64312
Synonyms
  • 1,3-Dimethyl-5-adamantanamine
  • 1-Amino-3,5-dimethyladamantane
  • 3,5-Dimethyl-1-adamantanamine
  • 3,5-Dimethyl-1-aminoadamantane
  • 3,5-dimethyladamantan-1-amine
  • 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
  • memantina
  • memantine
  • memantinum
Definition
A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
References
  • cas:19982-08-2
  • drugbank:DB01043
  • drugcentral:1679
  • kegg.compound:C13736
  • kegg.drug:D08174
  • lincs.smallmolecule:LSM-5154
  • patent:US2011282100
  • pubmed:20104942
  • pubmed:21953515
  • pubmed:21955815
  • pubmed:22030128
  • pubmed:22134197
  • pubmed:22245025
  • pubmed:22248638
  • pubmed:22290557
  • pubmed:22297273
  • pubmed:22300835
  • pubmed:22311362
  • pubmed:22327556
  • pubmed:22329473
  • pubmed:22392787
  • pubmed:22414570
  • pubmed:22425751
  • reaxys:2075983
  • wikipedia.en:Memantine
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from memantine
Phenotype where environments contain memantine
Phenotype modified by environments containing memantine
Phenotype affecting memantine
Human Disease Model