leupeptin

Term ID

CHEBI:6426

Synonyms

Ac-L-Leu-L-Leu-L-Arg-H
Ac-Leu-Leu-Arg-H
Ac-Leu-Leu-argininal
Ac-LLR-H
acetyl-L-leucyl-L-leucyl-L-argininal
N-acetyl-L-leucyl-L-leucyl-L-argininal
N-acetyl-L-leucyl-N-[(2S)-5-carbamimidamido-1-oxopentan-2-yl]-L-leucinamide
N-acetyl-leucylleucylargininal

(all 8)

Definition

A tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death.

References

(all 37)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aldehyde tripeptide

aldehyde tripeptide Show first 5 Terms
has_role: bacterial metabolite calpain inhibitor cathepsin B inhibitor EC 3.4.21.4 (trypsin) inhibitor serine protease inhibitor

bacterial metabolite calpain inhibitor cathepsin B inhibitor EC 3.4.21.4 (trypsin) inhibitor serine protease inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: leupeptin(1+)

leupeptin(1+) Show first 5 Terms
is_conjugate_base_of: leupeptin(1+)

leupeptin(1+) Show first 5 Terms

Phenotype

Phenotype resulting from leupeptin

Phenotype where environments contain leupeptin

Phenotype modified by environments containing leupeptin

Phenotype affecting leupeptin

Human Disease Model