metergoline

Term ID

CHEBI:64216

Synonyms

(((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid benzyl ester
(((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
(+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
benzyl {[(8alpha)-1,6-dimethylergolin-8-yl]methyl}carbamate
D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline benzyl ester
Metergolin
metergolina
metergoline
metergolinum

Definition

An ergoline alkaloid that is the N-benzyloxycarbonyl derivative of lysergamine. A 5-HT₂ antagonist. Also 5-HT₁ antagonist and 5-HT_1D ligand. Has moderate affinity for 5-HT₆ and high affinity for 5-HT₇.

References

cas:17692-51-2
drugcentral:1723
kegg.drug:D07218
lincs.smallmolecule:LSM-3265
pubmed:18996971
pubmed:19484723
pubmed:19509219
pubmed:19538518
pubmed:19539656
pubmed:19632276
pubmed:19945477
pubmed:20377624
pubmed:20451398
pubmed:20845263
pubmed:21354537
pubmed:21475142
pubmed:21600959
pubmed:21880033
pubmed:22218419
pubmed:24134630
reaxys:5362415
wikipedia.en:Metergoline

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from metergoline

Phenotype where environments contain metergoline

Phenotype modified by environments containing metergoline

Phenotype affecting metergoline

Human Disease Model