lapachol

Term ID

CHEBI:6377

Synonyms

• 2-hydroxy-3-(3-methyl-2-buten-1-yl)-1,4-naphthalenedione
• 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione
• 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone
• 2-hydroxy-3-(3-methylbut-2-en-1-yl)-1,4-dihydronaphthalene-1,4-dione
• 2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione
• Bethabarra wood
• C.I. 75490
• C.I. natural yellow 16
• greenhartin
• Ipe-tobacco wood
• Lapachol
• lapachol wood
• Surinam greenheart wood
• Taigu wood
• taiguic acid
• tecomin

Definition

A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.

References

• CAS:84-79-7
• Chemspider:10770962
• HMDB:HMDB0253978
• KEGG:C10366
• KNApSAcK:C00002835
• PMID:11180522
• PMID:30797783
• PMID:30896339
• PMID:31183610
• PMID:31935485
• PMID:32318101
• PMID:32712193
• PMID:33019942
• PMID:33254016
• PMID:33275860
• Wikipedia:Lapachol

Ontology

ChEBI  ( EBI )

Resources

CTD