Search Ontology:
ChEBI
tenofovir (anhydrous)
- Term ID
- CHEBI:63625
- Synonyms
-
- (R)-PMPA
- ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
- anh. tenofovir
- anhydrous tenofovir
- tenofovir
- tenofovir (anh.)
- Definition
- A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
- References
-
- cas:147127-20-6
- drugbank:DB00300
- hmdb:HMDB0014445
- kegg.drug:D06074
- lincs.smallmolecule:LSM-5340
- pubmed:11777298
- pubmed:25017682
- pubmed:28166217
- pubmed:28503983
- reaxys:7415378
- wikipedia.en:Tenofovir
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from tenofovir (anhydrous)
Phenotype where environments contain tenofovir (anhydrous)
Phenotype modified by environments containing tenofovir (anhydrous)
Phenotype affecting tenofovir (anhydrous)
Human Disease Model