(S)-fenfluramine hydrochloride

Term ID

CHEBI:59730

Synonyms

(+)-(S)-N-ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine hydrochloride
(+)-fenfluramine hydrochloride
(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride
(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-aminium chloride
dexfenfluramine HCl
dexfenfluramine hydrochloride
dextrofenfluramine hydrochloride

Definition

The hydrochloride salt of (S)-fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike the racemate it does not possess catecholamine agonist activity. It was formerly given by mouth in the treatment of obesity, but, like the racemate, was withdrawn wolrdwide following reports of valvular heart defects.

References

Beilstein:7114728
Beilstein:8165762
CAS:3239-45-0
DrugBank:DB01191
KEGG:D03713

Ontology

ChEBI ( EBI )

Relationships

is a type of: fenfluramine hydrochloride

fenfluramine hydrochloride Show first 5 Terms
has_part: (S)-fenfluramine

(S)-fenfluramine Show first 5 Terms
has_role: appetite depressant serotonergic agonist serotonin uptake inhibitor

appetite depressant serotonergic agonist serotonin uptake inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from (S)-fenfluramine hydrochloride

Phenotype where environments contain (S)-fenfluramine hydrochloride

Phenotype modified by environments containing (S)-fenfluramine hydrochloride

Human Disease Model