Search Ontology:
ChEBI
polymyxin
- Term ID
- CHEBI:59062
- Synonyms
-
- polymixin
- polymycin
- polymyxins
- Definition
- Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria.
- References
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from polymyxin
Phenotype where environments contain polymyxin
Phenotype modified by environments containing polymyxin
Phenotype affecting polymyxin
Human Disease Model