harman

Term ID

CHEBI:5623

Synonyms

• 1-methyl-2-carboline
• 1-methyl-9H-beta-carboline
• 1-methyl-9H-pyrido[3,4-b]indole
• 1-methyl-beta-carboline
• 1-methylnorharman
• aribin
• aribine
• Harman
• harmane
• L-methylpyridobindole
• locuturin
• locuturine
• loturine
• passiflorin

Definition

An indole alkaloid fundamental parent with a structure of 9H-β-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A.

References

• cas:486-84-0
• kegg.compound:C09209
• knapsack:C00001736
• lincs.smallmolecule:LSM-19989
• pubmed:11473435
• pubmed:19645722
• pubmed:20732341
• pubmed:22757671
• pubmed:22981972
• pubmed:23544153
• pubmed:24103378
• pubmed:24300779
• pubmed:24486683
• reaxys:143898

Ontology

ChEBI  ( EBI )

Resources

CTD