Search Ontology:
ChEBI
guanadrel
- Term ID
- CHEBI:5555
- Synonyms
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- 1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine
- guanadrel
- guanadrelum
- Definition
- A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
- References
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- Beilstein:8325419
- CAS:40580-59-4
- DrugBank:DB00226
- Drug_Central:1339
- HMDB:HMDB0014371
- KEGG:C07035
- KEGG:D08029
- PMID:3896742
- PMID:6621504
- PMID:7206175
- Patent:US3547951
- Reaxys:8325419
- Wikipedia:Guanadrel
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
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Phenotype
Phenotype resulting from guanadrel
Phenotype where environments contain guanadrel
Phenotype modified by environments containing guanadrel
Human Disease Model