esomeprazole

Term ID

CHEBI:50275

Synonyms

(-)-omeprazole
(S)-(-)-omeprazole
(S)-omeprazole
5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
Alenia
Escz
Esofag
esomeprazol
esomeprazole
esomeprazolum
Inexium paranova

Definition

A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.

References

CAS:119141-88-7
DrugBank:DB00736
Drug_Central:1055
HMDB:HMDB0005009
HMDB:HMDB0014874
KEGG:D07917
PMID:10983736
PMID:15080761
PMID:18407713
PMID:18472988
PMID:23677700
Reaxys:12060639
Wikipedia:Esomeprazole

Ontology

ChEBI ( EBI )

Relationships

is a type of: 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole

5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Show first 5 Terms
has_role: anti-ulcer drug EC 1.4.3.4 (monoamine oxidase) inhibitor EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor histamine antagonist

anti-ulcer drug EC 1.4.3.4 (monoamine oxidase) inhibitor EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor histamine antagonist Show first 5 Terms
inverse has_part: omeprazole

omeprazole Show first 5 Terms
inverse is_conjugate_base_of: esomeprazole(1-)

esomeprazole(1-) Show first 5 Terms
inverse is_enantiomer_of: (R)-omeprazole

(R)-omeprazole Show first 5 Terms
is_conjugate_acid_of: esomeprazole(1-)

esomeprazole(1-) Show first 5 Terms
is_enantiomer_of: (R)-omeprazole

(R)-omeprazole Show first 5 Terms

Phenotype

Phenotype resulting from esomeprazole

Phenotype where environments contain esomeprazole

Phenotype modified by environments containing esomeprazole

Human Disease Model