fumagillin

Term ID

CHEBI:48635

Synonyms

• (2E,4E,6E,8E)-10-({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]oct-6-yl}oxy)-10-oxodeca-2,4,6,8-tetraenoic acid
• 2,4,6,8-decatetraenedioic acid, 4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-1-oxaspiro(2,5)oct-6-yl ester
• Fugillin
• fumagilina
• Fumagillin
• fumagilline
• fumagillinum
• Fumidil

Definition

A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.

References

• cas:23110-15-8
• drugbank:DB02640
• drugcentral:3253
• kegg.compound:C09668
• knapsack:C00003133
• lipidmaps:LMPR0103060003
• patent:US2652356
• patent:US2803586
• pubmed:14514693
• pubmed:14809278
• pubmed:15723631
• pubmed:23121865
• pubmed:23488861
• pubmed:23505365
• reaxys:5360220
• wikipedia.en:Fumagillin

Ontology

ChEBI  ( EBI )

Resources

CTD