Search Ontology:
ChEBI

4-methyl-2-oxopentanoic acid

Term ID
CHEBI:48430
Synonyms
  • 2-OXO-4-METHYLPENTANOIC ACID
  • 2-Oxoisocaproate
  • 4-Methyl-2-oxopentanoate
  • 4-methyl-2-oxopentanoic acid
  • 4-methyl-2-oxovaleric acid
  • alpha-ketoisocaproic acid
  • Ketoleucine
Definition
A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.
References
  • cas:816-66-0
  • drugbank:DB03229
  • hmdb:HMDB0000695
  • kegg.compound:C00233
  • knapsack:C00019677
  • metacyc.compound:2K-4CH3-PENTANOATE
  • pdb-ccd:COI
  • pubmed:14636955
  • pubmed:22770225
  • reaxys:1701823
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from 4-methyl-2-oxopentanoic acid
Phenotype where environments contain 4-methyl-2-oxopentanoic acid
Phenotype modified by environments containing 4-methyl-2-oxopentanoic acid
Phenotype affecting 4-methyl-2-oxopentanoic acid
Human Disease Model
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