ecgonine

Term ID

CHEBI:4743

Synonyms

• (-)-Ecgonine
• (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid
• 1-Ecgonine
• 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylic acid
• 3beta-hydroxy-2beta-tropanecarboxylic acid
• [1R*-(Exo,exo)]-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid
• Ecgonine

Definition

A tropane alkaloid that consists of tropane bearing carboxy and hydroxy substituents at positions 2 and 3 respectively and having (1R,2R,3S,5S)-configuration. It is both a metabolite of and a precursor to cocaine.

References

• cas:481-37-8
• drugbank:DB01525
• kegg.compound:C10858
• knapsack:C00002291
• pubmed:11469854
• pubmed:20077067
• pubmed:22018173
• reaxys:83293
• wikipedia.en:Ecgonine

Ontology

ChEBI  ( EBI )

Resources

CTD