docetaxel anhydrous

Term ID

CHEBI:4672

Synonyms

4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
Docetaxel
Docetaxel anhydrous
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
TXL

(all 6)

Definition

A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.

References

Beilstein:4290183
CAS:114977-28-5
DrugBank:DB01248
KEGG:C11231
KEGG:D07866
PDBeChem:TXL
Patent:EP253738
Patent:US4814470
Wikipedia:Docetaxel

(all 9)

Ontology

ChEBI ( EBI )

Relationships

is a type of: secondary alpha-hydroxy ketone tetracyclic diterpenoid

secondary alpha-hydroxy ketone tetracyclic diterpenoid Show first 5 Terms
has_parent_hydride: taxane

taxane Show first 5 Terms
has_role: antimalarial antineoplastic agent photosensitizing agent

antimalarial antineoplastic agent photosensitizing agent Show first 5 Terms
inverse has_part: docetaxel trihydrate

docetaxel trihydrate Show first 5 Terms

Phenotype

Phenotype resulting from docetaxel anhydrous

Phenotype where environments contain docetaxel anhydrous

Phenotype modified by environments containing docetaxel anhydrous

Phenotype affecting docetaxel anhydrous

Human Disease Model