difloxacin

Term ID

CHEBI:4537

Synonyms

6-fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
difloxacin
difloxacine
difloxacino
difloxacinum

Definition

A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usually as the monohydrochloride salt) for the treatment of bacterial infections in dogs.

References

cas:98106-17-3
kegg.compound:C11234
kegg.drug:D07828
patent:EP131839
patent:US4730000
pubmed:19751946
pubmed:22751072
pubmed:23742101
pubmed:23962048
pubmed:25229385
pubmed:3800345
reaxys:5835542
vsdb:1841
wikipedia.en:Difloxacin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from difloxacin

Phenotype where environments contain difloxacin

Phenotype modified by environments containing difloxacin

Phenotype affecting difloxacin

Human Disease Model