Search Ontology:

ChEBI

methotrexate

Term ID

CHEBI:44185

Synonyms

4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Emtexate
Ledertrexate
methotrexate
methotrexatum
metotrexato
MTX
N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall

Definition

References

Beilstein:70669
CAS:59-05-2
DrugBank:DB00563
Drug_Central:1751
KEGG:C01937
KEGG:D00142
LINCS:LSM-5690
PDBeChem:MTX
Patent:US2512572
Wikipedia:Methotrexate

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: dicarboxylic acid monocarboxylic acid amide pteridines

dicarboxylic acid monocarboxylic acid amide pteridines Show first 5 Terms
has_functional_parent: L-glutamic acid

L-glutamic acid Show first 5 Terms
has_role: abortifacient antimetabolite antineoplastic agent antirheumatic drug dermatologic drug ... Show All 8 Terms

abortifacient antimetabolite antineoplastic agent antirheumatic drug dermatologic drug DNA synthesis inhibitor EC 1.5.1.3 (dihydrofolate reductase) inhibitor immunosuppressive agent Show first 5 Terms
inverse is_conjugate_base_of: methotrexate(1-)

methotrexate(1-) Show first 5 Terms
is_conjugate_acid_of: methotrexate(1-)

methotrexate(1-) Show first 5 Terms

Phenotype

Phenotype resulting from methotrexate

Phenotype where environments contain methotrexate

Phenotype modified by environments containing methotrexate

Human Disease Model