cidofovir anhydrous

Term ID

CHEBI:3696

Synonyms

• (S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid
• (S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine
• (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
• (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine
• (S)-HPMPC
• ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
• 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
• 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
• [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid
• CDV
• Cidofovir
• Cidofovir anhydrous

Definition

Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

References

• beilstein:5080484
• cas:113852-37-2
• drugbank:DB00369
• drugcentral:639
• kegg.compound:C06909
• patent:EP253412
• patent:US5142051
• wikipedia.en:Cidofovir

Ontology

ChEBI  ( EBI )

Resources

CTD