epothilone B

Term ID

CHEBI:31550

Synonyms

• (-)-epothilone B
• (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
• EPO 906
• Epo B
• EpoB
• epothilone B
• patupilona
• patupilone
• patupilonum

Definition

An epithilone that is epithilone D in which the double bond in the macrocyclic ring has been oxidised to the corresponding epoxide (the S,S stereoisomer).

References

• CAS:152044-54-7
• DrugBank:DB03010
• KEGG:C12154
• KNApSAcK:C00044747
• LIPID_MAPS_instance:LMPK04000041
• PDBeChem:EPB
• PMID:10831849
• PMID:21743064
• PMID:22234539
• PMID:22688083
• PMID:22918719
• PMID:23205945
• PMID:23214997
• PMID:23801302
• PMID:24374386
• PMID:24470546
• PMID:24583341
• PMID:24913659
• PMID:25694444
• PMID:25721485
• PMID:25765066
• PMID:25919223
• PMID:26081685
• PMID:26308485
• PMID:26316786
• Reaxys:7556514

Ontology

ChEBI  ( EBI )