colforsin daropate hydrochloride

Term ID

CHEBI:31429

Synonyms

• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl N,N-dimethyl-beta-alaninate hydrochloride
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-naphtho[2,1-b]pyran-6-yl N,N-dimethyl-beta-alaninate--hydrogen chloride
• 6-(3-dimethylaminopropionyl)forskolin hydrochloride
• Adehl
• colforsin dapropate
• colforsin dapropate HCl
• colforsin dapropate hydrochloride
• colforsin daropate HCl
• colforsin daropate hydrochloride
• NKH 477
• NKH-477
• NKH477

Definition

The hydrochloride salt of colforsin daropate. It is a drug used for the treatment of acute heart failure. It directly stimulates adenylate cyclase and produces positive inotropic and vasodilator effects accompanied by the increase in cellular cAMP.

References

• CAS:138605-00-2
• Drug_Central:729
• KEGG:D01697
• PMID:10217303
• PMID:10395020
• PMID:10511949
• PMID:10611416
• PMID:10874508
• PMID:11211758
• PMID:11250507
• PMID:11343575
• PMID:11357303
• PMID:11426771
• PMID:11574389
• PMID:11712370
• PMID:11954952
• PMID:14512698
• PMID:14988663
• PMID:15682800
• PMID:15797749
• PMID:16261335
• PMID:17715681
• PMID:26431344
• PMID:27020043
• PMID:7474547
• PMID:7509903
• PMID:8595080
• PMID:8612348
• PMID:8737628
• PMID:8810493
• PMID:9416762

Ontology

ChEBI  ( EBI )

Resources

CTD