bentiromide

Term ID

CHEBI:31263

Synonyms

• (S)-4-((2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)benzoic acid
• (S)-p-(alpha-benzamido-p-hydroxyhydrocinnamamido)benzoic acid
• 4-(N-benzoyl-L-tyrosylamino)benzoic acid
• 4-[(N-benzoyl-L-tyrosyl)amino]benzoic acid
• bentiromide
• bentiromido
• bentiromidum
• benzoyltyrosyl-p-aminobenzoic acid
• BT-PABA
• BTPABA
• N-benzoyl-L-tyrosyl-p-aminobenzoate
• N-benzoyl-L-tyrosyl-p-aminobenzoic acid
• PFD
• PFT

Definition

The dipeptide obtained by condensation of N-benzoyl-L-tyrosine with 4-aminobenzoic acid. Used as a noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy, it is given by mouth: the amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas.

References

• Beilstein:2910938
• CAS:37106-97-1
• DrugBank:DB00522
• Drug_Central:316
• KEGG:D01346
• Patent:DE2156835
• Patent:US3801562
• Wikipedia:Bentiromide

Ontology

ChEBI  ( EBI )